
When a young laborer escapes to the world aboveground, he discovers a violent land in which humans battle robots controlled by a power-hungry noble.

Living underground in Giha Village, Simon and Kamina dream of a life on the surface. When their home is invaded from above, it is up to them to activate the mysterious mecha Lagann and save their village.

Now that they've made it to the surface, Simon and Kamina must join together with Yoko and her village to defeat the Beastmen pursuing them.

Kamina and Simon must work together to defeat a dangerous new Beastman threat.

Team Gurren must work together with the eccentric Black Syblings to take down a Beastman foe on empty stomachs.

Team Gurren must find their way out of a strange underground village where Gunmen are worshipped as divine beings.

Continuing to the Gunmen rallying point, Team Gurren finds themselves on a strange hot springs getaway.

Thymilph, one of the Four Divine Generals of the mysterious Spiral King, arrives to support Viral's Enki, with the massive mobile Gunmen fortress, the Dai-Ganzan. Kamina and Simon pilot the Gurren-Lagann against seemingly overwhelming odds.

Having temporarily stalled Viral and Thymilph in the last skirmish, the Team Gurren and their newly arrived allies join forces as "Team Dai-Gurren" and launch a decisive strike against the regrouping Gunmen force.

Team Dai-Gurren managed to take control of the enemy fortress, but is still mourning the death of one of their own, especially Simon. After falling off a cliff, he notices a Gunman throw a capsule into a deep valley. Simon inspects it and finds he is able to open it with the same drill key he uses to pilot Lagann, and inside is a young human girl named Nia, but their introduction is cut short when an enemy Gunman appears.

Nia true identity is revealed, as she flaunts her authority to get rid of another one of the Four Divine Generals, Adiane. The members of the Great Gurren Brigade are now suspicious of Nia and her true intentions, but she is only concerned about the depressed Simon. Adiane later returns to finish them all off, with Lordgenome's blessing.
Available on: TV Tokyo, TV Aichi, TVQ, TV Osaka, TVh, TSC