
20-something Angus MacGyver creates a clandestine organization where he uses his knack for solving problems in unconventional ways to help prevent disasters from happening.

Angus MacGyver and Jack Dalton, special agents for the Department of External Services (DXS), join forces to recover a missing bioweapon that has the ability to destroy hundreds of thousands of people with one single drop.

MacGyver and the team attempt to rescue Sarah, Jack’s former CIA partner/ex-girlfriend who went missing in Venezuela after she obtained evidence to take down an international arms dealer.

MacGyver and the team are in Malaysia to extract a terrorist groups’ money man, Ralph, who holds key intel to an impending attack. But the mission goes south when the man is shot, and now, with only a driver’s license and hand sanitizer available, MacGyver must keep Ralph alive in order to learn the terrorists’ plans.

Mac and Jack partner with older versions of themselves, a Russian bomb programmer and his estranged handler, to shut down a Soviet-era warhead in Moscow. But when the antiquated computer needed to disable the warhead becomes inoperable, Mac must find a way to fix it with only duct tape and wire in time to prevent a new Cold War.

Using only an armrest, a curtain rod, and a toothpick, MacGyver must fix a sabotaged train in order to protect a whistleblower who has proof that her boss is selling weapons to U.S. enemies.

Using only a wrench and rope, MacGyver must diffuse a bomb set near the United Nations by his old nemesis, “The Ghost”, a notorious criminal whose work killed his mentor, and track him down before he strikes again.

MacGyver is tasked to go undercover as an inmate in a maximum security prison to break out El Noche, a notorious drug kingpin, using only batteries and salt, and track him to his cartel's secret location and dismantle it.

When MacGyver comes face to face with Murdoc, an international assassin hired to kill him, Mac must defend both himself and Bozer, armed with only a corkscrew and paper towel rolls. Also, Bozer feels completely betrayed when he finally learns Mac's true identity.

With only a chisel and matchbook, MacGyver and team must defend themselves the U.S. embassy workers in Latvia from extremists who are attempting to retrieve their leader. Also, Bozer faces a big decision now that he knows who Mac really is.

Mac and the team have no time to reminisce while visiting Mac’s and Bozer’s hometown when they immediately start searching for a kidnapped prodigy from Mac’s old middle school, Valerie.
Created by: Peter M. Lenkov
Available on: CBS